Scientists find hidden geometric code shaping how human DNA works

A new study from Northwestern University, led by biomedical engineer Vadim Backman, reveals a previously unknown "geometric code" embedded in the three-dimensional structure of human DNA. Unlike the traditional genetic code based on the sequence of chemical bases (A, C, T, G), this geometric code arises from the spatial folding and nanoscale organization of DNA within cells. These physical configurations form "packing domains" that act as memory nodes, enabling cells to compute, store, and regulate genetic activity dynamically. This discovery suggests that the genome functions not just as a static script but as a living computational system, with its shape playing a critical role in gene behavior and cellular memory. The research implies that evolution may have advanced complexity not solely through new genes but by optimizing the geometric arrangement of existing genetic material, enhancing information storage and retrieval. This geometric language could bridge biology and computation, paralleling principles seen in artificial intelligence. Moreover, the fidelity of this geometric code appears to degrade with age, potentially contributing to diseases